Apaf1 / NLRP1 (CARD)

Interactions between Apaf1 in detail and NLRP1 in detail (CARD)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vitro interaction
  DD1 DD2 Reference
Family DD1 DD2 Method Species Region Expression Species Region Expression
CARD Apaf1 Link NLRP1 GST fusion protein pull-down Not specified Not specified In vitro translation Not specified Not specified E.coli 11113115
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
CARD Apaf1 Link NLRP1 Co-immunoprecipitation HEK293 Not specified Full length Not specified Full length 11113115
CARD Apaf1 Link NLRP1 Co-immunoprecipitation HEK293 Not specified Not specified Not specified Not specified 17418785
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Functional Role
Family DD1 DD2 Method Death-related Death-unrelated Reference
CARD Apaf1 Link NLRP1 DAPI staining Apoptosis 11113115
(Link: click this icon to show interactions only between the two corresponding DDs)