Bcl-10 / Bcl-10 (CARD)

Interactions between Bcl-10 in detail and Bcl-10 in detail (CARD)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
CARD Bcl-10 Link Bcl-10 Co-immunoprecipitation HEK293 Human Full length Human Full length 10364242
CARD Bcl-10 Link Bcl-10 Co-immunoprecipitation HEK293 Human Full length Human 1-104 10364242
CARD Bcl-10 Link Bcl-10 Co-immunoprecipitation HEK293 Not specified Full length Human Full length 14638696
CARD Bcl-10 Link Bcl-10 Co-immunoprecipitation HEK293 Not specified 1-127 Not specified 1-127 19538180
CARD Bcl-10 Link Bcl-10 GST fusion protein pull-down HEK293 Human Full length Human Full length 10187815
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Characterization
  Stoichiometry Affinity Protein-Protein interface Reference
Family DD1 DD2 Method Mutation Complex structure
CARD Bcl-10 Link Bcl-10 Co-immunoprecipitation L41R(Bcl-10) 10364242
CARD Bcl-10 Link Bcl-10 Fluorescence probe labeling 3.0μM 19538180
CARD Bcl-10 Link Bcl-10 GST fusion protein pull-down L47A, I46A, L41A, I55A (Bcl-10) 10187815
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Functional Role
Family DD1 DD2 Method Death-related Death-unrelated Reference
CARD Bcl-10 Link Bcl-10 Luciferase assay NF-kB activation 10364242
(Link: click this icon to show interactions only between the two corresponding DDs)