Bcl-10 / CARD11 (CARD)
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In vitro interaction | |||||||||||||
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DD1 | DD2 | Reference | |||||||||||
Family | DD1 | DD2 | Method | Species | Region | Expression | Species | Region | Expression | ||||
CARD | Bcl-10 |
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CARD11 | GST fusion protein pull-down | Not specified | Not specified | E.coli | Not specified | 1-126 | In vitro translation | 11278692 | ||
CARD | Bcl-10 |
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CARD11 | In vitro purification protein assembly(chemical crosslinking) | Mouse | Not specified | E.coli | Mouse | 1-160 | E.coli | 20439115 | ||
CARD | Bcl-10 |
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CARD11 | Two-hybrid | Not specified | Not specified | HEK293 | Not specified | 1-126 | HEK293 | 11278692 |
(
: click this icon to show interactions only between the two corresponding DDs)

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In vivo interaction | |||||||||||||
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Endogenous expression |
Overexpression | DD1 | DD2 | Reference | |||||||||
Family | DD1 | DD2 | Method | Species | Region | Species | Region | ||||||
CARD | Bcl-10 |
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CARD11 | Co-Immunofluorescence staining | HeLa | Human | 2-233 | Human | 1-153 | 11356195 | |||
CARD | Bcl-10 |
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CARD11 | Co-immunoprecipitation | HEK293 | Not used | Not specified | 1-126 | 11278692 | ||||
CARD | Bcl-10 |
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CARD11 | Co-immunoprecipitation | HEK293 | Human | 2-233 | Human | 1-153 | 11356195 | |||
CARD | Bcl-10 |
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CARD11 | Co-immunoprecipitation | HEK293 | Not specified | Not specified | Not specified | Not specified | 12154360 | |||
CARD | Bcl-10 |
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CARD11 | Co-immunoprecipitation | HEK293 | Mouse | Not specified | Human | 1-470 | 16809782 | |||
CARD | Bcl-10 |
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CARD11 | Co-immunoprecipitation | Jurkat | 16818229 | |||||||
CARD | Bcl-10 |
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CARD11 | Co-immunoprecipitation | DO11.10 | 17478723 | |||||||
CARD | Bcl-10 |
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CARD11 | Co-immunoprecipitation | DT40 | Not used | Not specified | Not specified | 18086859 | ||||
CARD | Bcl-10 |
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CARD11 | Co-immunoprecipitation | DO11.10 | 18802088 | |||||||
CARD | Bcl-10 |
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CARD11 | Co-immunoprecipitation | Jurkat | 19444310 | |||||||
CARD | Bcl-10 |
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CARD11 | Co-immunoprecipitation | DLBCL | 19841089 | |||||||
CARD | Bcl-10 |
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CARD11 | Co-immunoprecipitation | Jurkat | 21157432 | |||||||
CARD | Bcl-10 |
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CARD11 | Co-immunoprecipitation | Jurkat | 21199863 |
(
: click this icon to show interactions only between the two corresponding DDs)

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Characterization | |||||||||||
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Stoichiometry | Affinity | Protein-Protein interface | Reference | ||||||||
Family | DD1 | DD2 | Method | Mutation | Complex structure | ||||||
CARD | Bcl-10 |
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CARD11 | Co-immunoprecipitation | L39R (CARD11) | 12154360 | |||||
CARD | Bcl-10 |
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CARD11 | Co-immunoprecipitation | S109A (CARD11) | 16809782 |
(
: click this icon to show interactions only between the two corresponding DDs)

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Functional Role | |||||||||||
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Family | DD1 | DD2 | Method | Death-related | Death-unrelated | Reference | |||||
CARD | Bcl-10 |
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CARD11 | Luciferase assay | Bcl10 phosphorylation, NF-kB activation (Signalosome) | 11356195 | |||||
CARD | Bcl-10 |
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CARD11 | Luciferase assay | NF-kB activation (signalosome) | 11278692 | |||||
CARD | Bcl-10 |
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CARD11 | Luciferase assay | NF-kB activation (Signalosome) | 12154360 | |||||
CARD | Bcl-10 |
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CARD11 | Luciferase assay | NF-kB activation (Signalosome) | 16809782 | |||||
CARD | Bcl-10 |
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CARD11 | Immunofluorescence staining | NF-kB activation (Signalosome) | 17478723 | |||||
CARD | Bcl-10 |
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CARD11 | Immunofluorescence staining | NF-kB activation (Signalosome) | 18802088 |
(
: click this icon to show interactions only between the two corresponding DDs)
