Bcl-10 / CARD11 (CARD)

Interactions between Bcl-10 in detail and CARD11 in detail (CARD)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vitro interaction
  DD1 DD2 Reference
Family DD1 DD2 Method Species Region Expression Species Region Expression
CARD Bcl-10 Link CARD11 GST fusion protein pull-down Not specified Not specified E.coli Not specified 1-126 In vitro translation 11278692
CARD Bcl-10 Link CARD11 In vitro purification protein assembly(chemical crosslinking) Mouse Not specified E.coli Mouse 1-160 E.coli 20439115
CARD Bcl-10 Link CARD11 Two-hybrid Not specified Not specified HEK293 Not specified 1-126 HEK293 11278692
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
CARD Bcl-10 Link CARD11 Co-Immunofluorescence staining HeLa Human 2-233 Human 1-153 11356195
CARD Bcl-10 Link CARD11 Co-immunoprecipitation HEK293 Not used Not specified 1-126 11278692
CARD Bcl-10 Link CARD11 Co-immunoprecipitation HEK293 Human 2-233 Human 1-153 11356195
CARD Bcl-10 Link CARD11 Co-immunoprecipitation HEK293 Not specified Not specified Not specified Not specified 12154360
CARD Bcl-10 Link CARD11 Co-immunoprecipitation HEK293 Mouse Not specified Human 1-470 16809782
CARD Bcl-10 Link CARD11 Co-immunoprecipitation Jurkat 16818229
CARD Bcl-10 Link CARD11 Co-immunoprecipitation DO11.10 17478723
CARD Bcl-10 Link CARD11 Co-immunoprecipitation DT40 Not used Not specified Not specified 18086859
CARD Bcl-10 Link CARD11 Co-immunoprecipitation DO11.10 18802088
CARD Bcl-10 Link CARD11 Co-immunoprecipitation Jurkat 19444310
CARD Bcl-10 Link CARD11 Co-immunoprecipitation DLBCL 19841089
CARD Bcl-10 Link CARD11 Co-immunoprecipitation Jurkat 21157432
CARD Bcl-10 Link CARD11 Co-immunoprecipitation Jurkat 21199863
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Characterization
  Stoichiometry Affinity Protein-Protein interface Reference
Family DD1 DD2 Method Mutation Complex structure
CARD Bcl-10 Link CARD11 Co-immunoprecipitation L39R (CARD11) 12154360
CARD Bcl-10 Link CARD11 Co-immunoprecipitation S109A (CARD11) 16809782
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Functional Role
Family DD1 DD2 Method Death-related Death-unrelated Reference
CARD Bcl-10 Link CARD11 Luciferase assay Bcl10 phosphorylation, NF-kB activation (Signalosome) 11356195
CARD Bcl-10 Link CARD11 Luciferase assay NF-kB activation (signalosome) 11278692
CARD Bcl-10 Link CARD11 Luciferase assay NF-kB activation (Signalosome) 12154360
CARD Bcl-10 Link CARD11 Luciferase assay NF-kB activation (Signalosome) 16809782
CARD Bcl-10 Link CARD11 Immunofluorescence staining NF-kB activation (Signalosome) 17478723
CARD Bcl-10 Link CARD11 Immunofluorescence staining NF-kB activation (Signalosome) 18802088
(Link: click this icon to show interactions only between the two corresponding DDs)