CARD12 / ASC (CARD)

Interactions between CARD12 in detail and ASC in detail (CARD)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vitro interaction
  DD1 DD2 Reference
Family DD1 DD2 Method Species Region Expression Species Region Expression
CARD CARD12 Link ASC GST fusion protein pull-down Human 1-88 E.coli Human 105-195 In vitro translation 11967258
CARD CARD12 Link ASC GST fusion protein pull-down Human 1-88 E.coli Human Full length In vitro translation 11967258
CARD CARD12 Link ASC Two-hybrid Not specified 1-83 HEK293 Not specified Not specified HEK293 11374873
CARD CARD12 Link ASC Yeast two-hybrid Human 1-96 Yeast Human Full length Yeast 19337385
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
CARD CARD12 Link ASC Co-immunoprecipitation HEK293 Not specified 1-647 Not specified Full length 12646168
CARD CARD12 Link ASC Co-immunoprecipitation HEK293 Human 1-457 Human Not specified 15701651
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Functional Role
Family DD1 DD2 Method Death-related Death-unrelated Reference
CARD CARD12 Link ASC β-galactosidase staining, Luciferase assay Apoptosis NF-kB activation 12646168
(Link: click this icon to show interactions only between the two corresponding DDs)