Caspase1 / CARD16 (CARD)

Interactions between Caspase1 in detail and CARD16 in detail (CARD)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vitro interaction
  DD1 DD2 Reference
Family DD1 DD2 Method Species Region Expression Species Region Expression
CARD Caspase1 Link CARD16 GST fusion protein pull-down Not specified Not specified In vitro translation Human 1-106 E.coli 11536016
CARD Caspase1 Link CARD16 GST fusion protein pull-down Not specified Not specified In vitro translation Not specified Not specified E.coli 11821383
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
CARD Caspase1 Link CARD16 Co-immunoprecipitation HEK293 Not specified Full length Human Not specified 11432859
CARD Caspase1 Link CARD16 Co-immunoprecipitation HEK293 Not specified 1-120 Human Not specified 11432859
CARD Caspase1 Link CARD16 Co-immunoprecipitation HEK293 Not specified Not specified Human 1-106 11536016
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Functional Role
Family DD1 DD2 Method Death-related Death-unrelated Reference
CARD Caspase1 Link CARD16 Immunoprecipitation, ELISA Rip mediated procaspase1 oligomerization inhibition, IL-1b secretion decrease 11432859
CARD Caspase1 Link CARD16 Immunoprecipitation Caspase1-RIPK2 complex interfere 11536016
(Link: click this icon to show interactions only between the two corresponding DDs)