Caspase1 / CARD8 (CARD)

Interactions between Caspase1 in detail and CARD8 in detail (CARD)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vitro interaction
  DD1 DD2 Reference
Family DD1 DD2 Method Species Region Expression Species Region Expression
CARD Caspase1 Link CARD8 GST fusion protein pull-down Not specified Not specified In vitro translation Not specified Full length E.coli 11821383
CARD Caspase1 Link CARD8 Yeast two-hybrid Human 1-91 Yeast Human 342-430 Yeast 19337385
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
CARD Caspase1 Link CARD8 Co-immunoprecipitation HEK293 Not specified Not specified Not specified Full length 11821383
CARD Caspase1 Link CARD8 Co-immunoprecipitation HEK293 Not specified Full length Not specified Not specified 11821383
CARD Caspase1 Link CARD8 Co-immunoprecipitation HEK293 Not specified Not specified Not specified 320-431 15030775
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Functional Role
Family DD1 DD2 Method Death-related Death-unrelated Reference
CARD Caspase1 Link CARD8 Caspase cleaved assay, ELISA Caspase1 activation block, IL-1b secretion decrease 11821383
(Link: click this icon to show interactions only between the two corresponding DDs)