Caspase1 / NLRP1 (CARD)

Interactions between Caspase1 in detail and NLRP1 in detail (CARD)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
CARD Caspase1 Link NLRP1 Co-immunoprecipitation HEK293 Human Not specified Human Full length 17349957
CARD Caspase1 Link NLRP1 Co-immunoprecipitation HEK293 Not specified Not specified Not specified Not specified 17418785
CARD Caspase1 Link NLRP1 Co-immunoprecipitation Rat cortical lysate 19401709
CARD Caspase1 Link NLRP1 Co-immunoprecipitation HEK293 Not specified Not specified Not specified Not specified 21252346
CARD Caspase1 Link NLRP1 Size-exclusion chromatography Mice cerebral cortex 19066616
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Functional Role
Family DD1 DD2 Method Death-related Death-unrelated Reference
CARD Caspase1 Link NLRP1 Luciferase assay Caspase1 activation (Inflammasome) 17349957
CARD Caspase1 Link NLRP1 ELISA IL-1b secretion increase 17418785
CARD Caspase1 Link NLRP1 Caspase cleaved assay Caspase1 activation (Inflammasome) 21252346
(Link: click this icon to show interactions only between the two corresponding DDs)