NLRP1 / Caspase1 (CARD)
 In vitro interaction
In vivo interaction
Characterization
Functional role
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| In vivo interaction | |||||||||||||
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| Endogenous expression |
Overexpression | DD1 | DD2 | Reference | |||||||||
| Family | DD1 | DD2 | Method | Species | Region | Species | Region | ||||||
| CARD | NLRP1 |
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Caspase1 | Co-immunoprecipitation | HEK293 | Human | Full length | Human | Not specified | 17349957 | |||
| CARD | NLRP1 |
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Caspase1 | Co-immunoprecipitation | HEK293 | Not specified | Not specified | Not specified | Not specified | 17418785 | |||
| CARD | NLRP1 |
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Caspase1 | Co-immunoprecipitation | Rat cortical lysate | 19401709 | |||||||
| CARD | NLRP1 |
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Caspase1 | Co-immunoprecipitation | HEK293 | Not specified | Not specified | Not specified | Not specified | 21252346 | |||
| CARD | NLRP1 |
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Caspase1 | Size-exclusion chromatography | Mice cerebral cortex | 19066616 | |||||||
(: click this icon to show interactions only between the two corresponding DDs)
: click this icon to show interactions only between the two corresponding DDs)
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In vitro interaction
In vivo interaction
Characterization
Functional role
|
top
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| Functional Role | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Family | DD1 | DD2 | Method | Death-related | Death-unrelated | Reference | |||||
| CARD | NLRP1 |
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Caspase1 | Luciferase assay | Caspase1 activation (Inflammasome) | 17349957 | |||||
| CARD | NLRP1 |
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Caspase1 | ELISA | IL-1b secretion increase | 17418785 | |||||
| CARD | NLRP1 |
|
Caspase1 | Caspase cleaved assay | Caspase1 activation (Inflammasome) | 21252346 | |||||
(: click this icon to show interactions only between the two corresponding DDs)
: click this icon to show interactions only between the two corresponding DDs)
