NOD2 / RIG-1 (CARD)

Interactions between NOD2 in detail and RIG-1 in detail (CARD)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vitro interaction
  DD1 DD2 Reference
Family DD1 DD2 Method Species Region Expression Species Region Expression
CARD NOD2 Link RIG-1 His Fusion protein pull-down Not specified 1-301 E.coli Not specified 1-205 E.coli 21690088
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
CARD NOD2 Link RIG-1 Co-Immunofluorescence staining HT29 21690088
CARD NOD2 Link RIG-1 Co-Immunofluorescence staining HEK293 Not specified Not specified Not specified Not specified 21690088
CARD NOD2 Link RIG-1 Co-immunoprecipitation HEK293 Not specified Full length Not specified Full length 21690088
CARD NOD2 Link RIG-1 Co-immunoprecipitation HEK293 Not specified 1-301 Not specified Full length 21690088
CARD NOD2 Link RIG-1 Co-immunoprecipitation HEK293 Not specified 1-301 Not specified 1-225 21690088
CARD NOD2 Link RIG-1 Co-immunoprecipitation HEK293 Not specified Full length Not specified 1-225 21690088
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Functional Role
Family DD1 DD2 Method Death-related Death-unrelated Reference
CARD NOD2 Link RIG-1 Reporter gene assay NF-kB activation block, IFN-b activation block 21690088
(Link: click this icon to show interactions only between the two corresponding DDs)