FADD / DR5 (DD)

Interactions between FADD in detail and DR5 in detail (DD)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vitro interaction
  DD1 DD2 Reference
Family DD1 DD2 Method Species Region Expression Species Region Expression
DD FADD Link DR5 GST fusion protein pull-down Jurkat lysate Not specified 191-411 E.coli 12721308
DD FADD Link DR5 GST fusion protein pull-down HeLa lysate Not specified 209-411 E.coli 12920112
DD FADD Link DR5 Yeast two-hybrid Not specified Full length Yeast Not specified 209-412 Yeast 15173180
DD FADD Link DR5 Yeast two-hybrid Not specified Full length Yeast Not specified 209-412 Yeast 15452120
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
DD FADD Link DR5 Co-immunoprecipitation HEK293 Human Not specified Human 51-411 9430227
DD FADD Link DR5 Co-immunoprecipitation HEK293 Not specified 80-208 Not specified 232-439 9430228
DD FADD Link DR5 Co-immunoprecipitation BJAB 15173180
DD FADD Link DR5 Co-immunoprecipitation HeLa Not specified 272-469 Not specified 79-208 15173180
DD FADD Link DR5 Co-immunoprecipitation BJAB Not specified Full length Not specified 209-412 15452120
DD FADD Link DR5 Co-immunoprecipitation HepG2 16980609
DD FADD Link DR5 Co-immunoprecipitation HeLa 17585340
DD FADD Link DR5 Co-immunoprecipitation SW948 21272366
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Functional Role
Family DD1 DD2 Method Death-related Death-unrelated Reference
DD FADD Link DR5 β-galactosidase staining Apoptosis (DISC) 9430227
DD FADD Link DR5 Cytoplasmic histone associated DNA fragment detection Apoptosis (DISC) 9430228
DD FADD Link DR5 Caspase cleaved assay Caspase8 activation 15452120
DD FADD Link DR5 Immunofluorescence staining Apoptosis (DISC) 21272366
DD FADD Link DR5 Annexin V staining Apoptosis (DISC) 12920112
(Link: click this icon to show interactions only between the two corresponding DDs)