FADD / TRADD (DD)

Interactions between FADD in detail and TRADD in detail (DD)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vitro interaction
  DD1 DD2 Reference
Family DD1 DD2 Method Species Region Expression Species Region Expression
DD FADD Link TRADD GST fusion protein pull-down Not specified Full length E.coli Not specified 243-455 In vitro translation 16006552
DD FADD Link TRADD Yeast two-hybrid Not specified Full length Yeast Not specified Full length Yeast 8565075
DD FADD Link TRADD Yeast two-hybrid Not specified Full length Yeast Not specified 55-312 Yeast 8565075
DD FADD Link TRADD Yeast two-hybrid Not specified Full length Yeast Not specified 195-312 Yeast 8565075
DD FADD Link TRADD Yeast two-hybrid Not specified 92-208 Yeast Not specified 195-312 Yeast 8642271
DD FADD Link TRADD Yeast two-hybrid Human 80-208 Yeast Human Full length Yeast 11464214
DD FADD Link TRADD Yeast two-hybrid Not specified Full length Yeast Not specified Full length Yeast 12107169
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
DD FADD Link TRADD Co-Immunofluorescence staining Human TLE hammacampus section 16919273
DD FADD Link TRADD Co-immunoprecipitation HEK293 Not specified Full length Not specified Full length 8565075
DD FADD Link TRADD Co-immunoprecipitation HeLa Not specified 19-753 Not specified 195-312 8642271
DD FADD Link TRADD Co-immunoprecipitation HeLa 10521396
DD FADD Link TRADD Co-immunoprecipitation HEK293 Not specified Not specified Not specified Not specified 10521396
DD FADD Link TRADD Co-immunoprecipitation COS-7 Not specified Not specified Not specified Not specified 12796506
DD FADD Link TRADD Co-immunoprecipitation Human TLE hammacampus lysate 16919273
DD FADD Link TRADD Co-immunoprecipitation Mouse seizure hippocampal 21760970
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Characterization
  Stoichiometry Affinity Protein-Protein interface Reference
Family DD1 DD2 Method Mutation Complex structure
DD FADD Link TRADD GST fusion protein pull-down D246R, E255R, Q267A, R278A (TRADD) R113E, R117E, D123R, D175R (FADD) 16006552
(Link: click this icon to show interactions only between the two corresponding DDs)