Myd88 / IRAK1 (DD)

Interactions between Myd88 in detail and IRAK1 in detail (DD)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
DD Myd88 Link IRAK1 Co-immunoprecipitation HEK293 Not specified 1-151 Not specified Full length 9430229
DD Myd88 Link IRAK1 Co-immunoprecipitation HEK293 Not specified 1-151 Not specified Full length 10383454
DD Myd88 Link IRAK1 Co-immunoprecipitation THP-1 10811644
DD Myd88 Link IRAK1 Co-immunoprecipitation HEK293 Not specified 1-172 Not specified Not specified 10854325
DD Myd88 Link IRAK1 Co-immunoprecipitation HEK293 Human Full length Human 1-215 11960013
DD Myd88 Link IRAK1 Co-immunoprecipitation HEK293 11976320
DD Myd88 Link IRAK1 Co-immunoprecipitation PC12 12034707
DD Myd88 Link IRAK1 Co-immunoprecipitation HEK293 Human Not specified Human Not specified 16024789
DD Myd88 Link IRAK1 Co-immunoprecipitation HEK293 Not specified Not specified Human Full length 17276401
DD Myd88 Link IRAK1 Co-immunoprecipitation HEK293 Not specified Not specified Human 2-109 17276401
DD Myd88 Link IRAK1 Co-immunoprecipitation Rat thoracic aortas derived vascular smooth muscle cell Not specified 1-306 Not specified 1-710 17510469
DD Myd88 Link IRAK1 Co-immunoprecipitation MT2 17920759
DD Myd88 Link IRAK1 Co-immunoprecipitation HUT102 17920759
DD Myd88 Link IRAK1 Co-immunoprecipitation MT4 17920759
DD Myd88 Link IRAK1 Co-immunoprecipitation HEK293 Not specified Not specified Human 2-712 18524972
DD Myd88 Link IRAK1 Co-immunoprecipitation HEK293 Not specified Not specified Not specified Not specified 19679662
DD Myd88 Link IRAK1 Co-immunoprecipitation HEK293 Not specified Not specified Not specified 27-72 19679662
DD Myd88 Link IRAK1 Co-immunoprecipitation HEK293 Not specified 27-72 Not specified Not specified 19679662
DD Myd88 Link IRAK1 Co-immunoprecipitation GCB DLBCL line BAJB Not specified Not specified Not used 21179087
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Characterization
  Stoichiometry Affinity Protein-Protein interface Reference
Family DD1 DD2 Method Mutation Complex structure
DD Myd88 Link IRAK1 Co-immunoprecipitation E52A and E53A, Y58A, K95A (Myd88) 19679662
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Functional Role
Family DD1 DD2 Method Death-related Death-unrelated Reference
DD Myd88 Link IRAK1 Luciferase assay NF-kB activation 9430229
DD Myd88 Link IRAK1 Luciferase assay NF-kB-activation 19679662
(Link: click this icon to show interactions only between the two corresponding DDs)