Myd88 / IRAK2 (DD)

Interactions between Myd88 in detail and IRAK2 in detail (DD)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vitro interaction
  DD1 DD2 Reference
Family DD1 DD2 Method Species Region Expression Species Region Expression
DD Myd88 Link IRAK2 GST fusion protein pull-down Not specified 1-296 E.coli Not specified Full length In vitro translation 12659850
DD Myd88 Link IRAK2 GST fusion protein pull-down Not specified 1-109 E.coli Not specified Full length In vitro translation 12659850
DD Myd88 Link IRAK2 GST fusion protein pull-down Not specified 1-155 E.coli Not specified Full length In vitro translation 12659850
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
DD Myd88 Link IRAK2 Co-immunoprecipitation HEK293 Human Full length Human Full length 9374458
DD Myd88 Link IRAK2 Co-immunoprecipitation HEK293 Not specified 1-151 Not specified Full length 10383454
DD Myd88 Link IRAK2 His fusion protein pull-down E.coli Human 20-117 Human 1-112 20485341
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Characterization
  Stoichiometry Affinity Protein-Protein interface Reference
Family DD1 DD2 Method Mutation Complex structure
DD Myd88 Link IRAK2 Structure 6:4:4 3MOP 20485341
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Functional Role
Family DD1 DD2 Method Death-related Death-unrelated Reference
DD Myd88 Link IRAK2 Luciferase assay NF-kB activation (Myddosome) 9374458
(Link: click this icon to show interactions only between the two corresponding DDs)