TRADD / FADD (DD)

Interactions between TRADD in detail and FADD in detail (DD)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vitro interaction
  DD1 DD2 Reference
Family DD1 DD2 Method Species Region Expression Species Region Expression
DD TRADD Link FADD GST fusion protein pull-down Not specified 243-455 In vitro translation Not specified Full length E.coli 16006552
DD TRADD Link FADD Yeast two-hybrid Not specified Full length Yeast Not specified Full length Yeast 8565075
DD TRADD Link FADD Yeast two-hybrid Not specified 55-312 Yeast Not specified Full length Yeast 8565075
DD TRADD Link FADD Yeast two-hybrid Not specified 195-312 Yeast Not specified Full length Yeast 8565075
DD TRADD Link FADD Yeast two-hybrid Not specified 195-312 Yeast Not specified 92-208 Yeast 8642271
DD TRADD Link FADD Yeast two-hybrid Human Full length Yeast Human 80-208 Yeast 11464214
DD TRADD Link FADD Yeast two-hybrid Not specified Full length Yeast Not specified Full length Yeast 12107169
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
DD TRADD Link FADD Co-Immunofluorescence staining Human TLE hammacampus section 16919273
DD TRADD Link FADD Co-immunoprecipitation HEK293 Not specified Full length Not specified Full length 8565075
DD TRADD Link FADD Co-immunoprecipitation HeLa Not specified 195-312 Not specified 19-753 8642271
DD TRADD Link FADD Co-immunoprecipitation HeLa 10521396
DD TRADD Link FADD Co-immunoprecipitation HEK293 Not specified Not specified Not specified Not specified 10521396
DD TRADD Link FADD Co-immunoprecipitation COS-7 Not specified Not specified Not specified Not specified 12796506
DD TRADD Link FADD Co-immunoprecipitation Human TLE hammacampus lysate 16919273
DD TRADD Link FADD Co-immunoprecipitation Mouse seizure hippocampal 21760970
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Characterization
  Stoichiometry Affinity Protein-Protein interface Reference
Family DD1 DD2 Method Mutation Complex structure
DD TRADD Link FADD GST fusion protein pull-down D246R, E255R, Q267A, R278A (TRADD) R113E, R117E, D123R, D175R (FADD) 16006552
(Link: click this icon to show interactions only between the two corresponding DDs)