ASC / NLRP10 (PYD)
 In vitro interaction
In vivo interaction
Characterization
Functional role
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| In vivo interaction | |||||||||||||
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| Endogenous expression |
Overexpression | DD1 | DD2 | Reference | |||||||||
| Family | DD1 | DD2 | Method | Species | Region | Species | Region | ||||||
| PYD | ASC |
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NLRP10 | Co-Immunofluorescence staining | HEK293 | 20393137 | |||||||
| PYD | ASC |
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NLRP10 | Co-immunoprecipitation | HEK293 | Human | Not specified | Human | Not specified | 15096476 | |||
(: click this icon to show interactions only between the two corresponding DDs)
: click this icon to show interactions only between the two corresponding DDs)
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In vitro interaction
In vivo interaction
Characterization
Functional role
|
top
|
| Functional Role | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Family | DD1 | DD2 | Method | Death-related | Death-unrelated | Reference | |||||
| PYD | ASC |
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NLRP10 | Propidium iodide-Annexin V staining, Luciferase assay, Immunostaining | Apoptosis inhibition | NF-kB-activation block, ASC aggregation inhibition | 20393137 | ||||
| PYD | ASC |
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NLRP10 | Annexin V staining, EMSA | ASC mediated Apoptosis block | NF-kB-activation block | 15096476 | ||||
(: click this icon to show interactions only between the two corresponding DDs)
: click this icon to show interactions only between the two corresponding DDs)
