ASC / NLRP10 (PYD)

Interactions between ASC in detail and NLRP10 in detail (PYD)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
PYD ASC Link NLRP10 Co-Immunofluorescence staining HEK293 20393137
PYD ASC Link NLRP10 Co-immunoprecipitation HEK293 Human Not specified Human Not specified 15096476
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Functional Role
Family DD1 DD2 Method Death-related Death-unrelated Reference
PYD ASC Link NLRP10 Propidium iodide-Annexin V staining, Luciferase assay, Immunostaining Apoptosis inhibition NF-kB-activation block, ASC aggregation inhibition 20393137
PYD ASC Link NLRP10 Annexin V staining, EMSA ASC mediated Apoptosis block NF-kB-activation block 15096476
(Link: click this icon to show interactions only between the two corresponding DDs)