ASC / NLRP10 (PYD)
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In vivo interaction | |||||||||||||
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Endogenous expression |
Overexpression | DD1 | DD2 | Reference | |||||||||
Family | DD1 | DD2 | Method | Species | Region | Species | Region | ||||||
PYD | ASC |
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NLRP10 | Co-Immunofluorescence staining | HEK293 | 20393137 | |||||||
PYD | ASC |
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NLRP10 | Co-immunoprecipitation | HEK293 | Human | Not specified | Human | Not specified | 15096476 |
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: click this icon to show interactions only between the two corresponding DDs)

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Functional Role | |||||||||||
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Family | DD1 | DD2 | Method | Death-related | Death-unrelated | Reference | |||||
PYD | ASC |
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NLRP10 | Propidium iodide-Annexin V staining, Luciferase assay, Immunostaining | Apoptosis inhibition | NF-kB-activation block, ASC aggregation inhibition | 20393137 | ||||
PYD | ASC |
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NLRP10 | Annexin V staining, EMSA | ASC mediated Apoptosis block | NF-kB-activation block | 15096476 |
(
: click this icon to show interactions only between the two corresponding DDs)
