CARD6 (CARD)

Full Name:
Caspase recruitment domain-containing protein 6
Alternative Names:
CINCIN1
Function:
May be involved in apoptosis.
Death Domain Subfamily & Boundary Region:
Species External DB Questionmark
Uniprot DIP STRING KEGG IntAct MINT
Human Seq Q9BX69external db link Q9BX69external db link hsa:84674external db link
Rat Seq D3ZVT3external db link rno:294770external db link
Dog Seq F1PIZ1external db link
Not solved yet
No information
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
CARD CARD6 Link CARD8 Co-immunoprecipitation HEK293 Human 1-311 Human Full length 12775719
CARD CARD6 Link NLRP1 Co-immunoprecipitation HEK293 Human 1-311 Not specified Full length 12775719
CARD CARD6 Link NOD1 Co-immunoprecipitation HEK293 Human 1-311 Not specified Not specified 12775719
CARD CARD6 Link RIPK2 Co-immunoprecipitation HEK293 Human 1-311 Not specified Not specified 12775719
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Functional Role
Family DD1 DD2 Method Death-related Death-unrelated Reference
CARD CARD6 Link NOD1 Luciferase assay NF-kB activation block 12775719
CARD CARD6 Link RIPK2 Luciferase assay NF-kB activation block 12775719
(Link: click this icon to show interactions only between the two corresponding DDs)