Caspase5 (CARD)

Full Name:
Caspase-5
Alternative Names:
ICH-3, MGC141966, ICEREL-III, ICE(rel)III, CASP5
Function:
Mediator of programmed cell death (apoptosis).
Death Domain Subfamily & Boundary Region:
Species External DB Questionmark
Uniprot DIP STRING KEGG IntAct MINT
Human Seq P51878external db link DIP-40038Nexternal db link P51878external db link hsa:838external db link P51878external db link
Not solved yet
No information
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
In vivo interaction
  Endogenous
expression
Overexpression DD1 DD2 Reference
Family DD1 DD2 Method Species Region Species Region
CARD Caspase5 Link NLRP1 Co-immunoprecipitation HEK293 Not specified Not specified Not specified Not specified 12191486
CARD Caspase5 Link NLRP1 Co-immunoprecipitation HEK293 Not specified Not specified Not specified Not specified 17418785
(Link: click this icon to show interactions only between the two corresponding DDs)
Arrow2 In vitro interaction Arrow2 In vivo interaction Arrow2 Characterization Arrow2 Functional role Arrow2 top
Functional Role
Family DD1 DD2 Method Death-related Death-unrelated Reference
CARD Caspase5 Link NLRP1 Caspase cleaved assay Caspase5 activation (Inflammasome) 12191486
CARD Caspase5 Link NLRP1 ELISA IL-1b secretion increase 17418785
(Link: click this icon to show interactions only between the two corresponding DDs)