UNC5A (DD)

Full Name:
Netrin receptor UNC5A
Alternative Names:
UNC5H1, FLJ16449, KIAA1976
Function:
Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.
Death Domain Subfamily & Boundary Region:
  • DD : 761-841 Seq
Species External DB Questionmark
Uniprot DIP STRING KEGG IntAct MINT
Human Seq Q6ZN44external db link Q6ZN44external db link hsa:90249external db link
Mouse Seq Q8K1S4external db link Q8K1S4external db link mmu:107448external db link
Rat Seq O08721external db link O08721external db link rno:60629external db link
Dog Seq F1P899external db link
Zebra fish Seq A5WZG2external db link
Not solved yet
No information
Question There is no death-domain PPI with UNC5A in Death Domain DD subfamily.