- At a glance
- In detail
- Full Name:
- Netrin receptor UNC5D
- Alternative Names:
- Unc5h4, FLJ16019, KIAA1777, PRO34692
- Receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity).
- Death Domain Subfamily & Boundary Region:
- DD : 859-936
Not solved yet
There is no death-domain PPI with UNC5D in Death Domain DD subfamily.